When you drink too much caffeine (aka energy drinks, coffee) and it makes you want to pee so bad it feels like your balls are in a vice.
"Omg, the energy drink just kicked in. I've got a mad case of ball vice."
by jDilLA June 21, 2007
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Somebody else has cornered you into a really tough situation, where you must now make a major decision between two things neither of which you want in the least.
They had his balls in a vice: either take the pay cut they were demanding from him, or be fired.
by Buddy4k4 July 25, 2017
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When you do something super bad to yourself, i.e. place your testicles in a vice
"Did we really leave the EU?" "Yeah bro, really stuck our balls in a vice on that one"
by Bullii June 24, 2016
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When someone is being a total dick or having a serious hateful/rude attitude towards everything/everyone.
Dude, you're being totally rude. What has your balls in a vice?
by emerald_gremlin September 14, 2017
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1)When someone encounters a particularly difficult situation.

2)Or when a male has his genitals placed in a piece of apperatus owned by a carpenter.
1) Man, this court case has my balls in a vice-grip.
by JJ November 25, 2003
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When a man is under extreme stress or pressure, usually from a female, due to a mistake or deadline.
Damn, my girl has my *balls in a vice grip* because I cheated on her.
by Devil421 November 26, 2003
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Zappa:"She had my balls in a vice but she left the dick, I guess it's still hooked on but now it shoots too quick. Oh god I am the american dream, but now I smell like Vaseline and I'm a miserable son of a bitch, am I a boy or a lady, I don't know which."
by Ghostwriter4u November 26, 2003
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