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ASSUME (ass u me) 

Assume and you think you know what somebody wants or needs, you’ll be wrong
When you ASSUME (ass u me) you make a ‘ass’ out of ‘u’ and ‘me’
ASSUME (ass u me) by Ramin99 September 22, 2018
(Contraction - Ass + Issues) An unfavorable or unpleasant state or condition of one's asshole. May be caused by Hemorrhoids, bad ass hygiene or that Habanero soaked enchilada from last night.
Dude, you got any Tucks, or Prep-H? I'm having some serious assues today.
Assues by MaxfieldP June 21, 2006
to make an ass out of u and me.
verb. To believe something is true based upon general unproven observations and reports.
Coining up a foolish, humorous insinuation about somebody or something that is probably not valid.
To make a complete idiot out of yourself or another person by saying that something happened that didn't.
I am assuming we're going to have wonderful weather today.
Assume.
Assume by Notmad February 17, 2013

Assumed Single 

After a long relationship and you get left on “read”; thus insinuating the relationship is over
Wow, Adam’s girl left him on read after a 2 year relationship. He’s assumed single now!

Assumehole 

An aggressive attacker on an issue spewing hatred at every response as if it was a direct and personal opposition.
Just don't engage an assumehole they will loose steam after a while when getting ignored.
Assumehole by The 80/20 rule July 28, 2017

Assume the Jess Neville 

The act of lying flat on the ground with arms by your sides, when either ordered to do so or as an agreed forfeit in a drinking game.

Originally started in Bristol after a viral video contained original footage of the Jess Neville assumption.
The official call is: "assume the jess neville!" at which point, unless one person has been targeted, everyone must assume the aforementioned position.

Assuming the jess neville can also be used as a punishment in drinking games until all but the winner has assumed the position.