Acquired immune deficiency syndrome is a disease which is slow and painful to kill.
Its also a weight loss drug found commonly in Africa.
To fall short of success or achievement in something expected, attempted, desired, or approved.
AIDS and FAIL.
Combine the two and you get a creamy delicious filling of slow and painful death by ones own incompetence and/or stupidity.
Tommy: "Dude that shit is so lame that it's filled with AIDS and FAIL!"