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1.
The feeling or sensation you have after taking a hit of weed and having someone squeeze you around the chest from behind while holding your breath.
After a long night of being Zizzled, young Troy decided to call it a night.
by Mojo Maniac July 10, 2008
 
2.
The after affects of smoking a fattie.
Christine was Zizzled after smoking a blunt
by DaveWehadababyitsaboy November 03, 2006