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Acronym in the internet startup community for "you only hit one million once", referring to obtaining your first million users.

Originates from yolo, but instead of the battle cry for moronic decisions, events prefixed or suffixed with YOHOMO tend to be related to first world problems.
Jason: Our 1M user party is going to be a disaster: we're out of fridge space for the Svedka.

Matt: Bro, just expense a new fridge. #YOHOMO.
YOHOMO by Phronesis December 13, 2012
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a super gay girl who can't admit that she's gay even though everybody knows it and calls her out on it
"yo, check out that girl right there! so gay!"
"YOHOMO!!!!!"
yohomo by justsayin69696 August 14, 2012
Related Words

Yohohohoho 

The shrill, strange, contagious sound that Brook from the anime "One Piece" makes when he laughs.
Brook (English Translation): "It has been over a few decades since I have eaten anything decent. It became so painful that the back of my stomach and my back were almost indistinguishable. That was the kind of life I lived for so many years. Then again, I am a skeleton so I don't have a stomach or back. Yohohohohohohohoho... SKULL JOKE!"
Yohohohoho by Holidaykay August 7, 2010
A laugh made known by The Gentleman Skeleton,Brook.
Yohoho,girl.Would you let me see your panties?
Yohoho by 7tyseven October 30, 2007

yofomoious 

"Thats really yofomoious!" and "He is really yofomoious." and "He's really smart,no he's yofomoious."
yofomoious by Jordan Cummins December 28, 2007
Raps shit that makes your thoughts connect to the nerves of your spirit making you elevate to the next level of consciousness connection in unity with our ancient destiny

One Love
"Ey, what's good yohomie"

"yo I'm good home, yo you good homie?"

"ye homie you know I'm good cuz, I'm yohomie"

"yo is that yohomie?"
yohomie by Ottomus Fresko October 18, 2018
"Move the car at the 45 m.p.h limit you yohoo."
Yohoo by Elite Enemy December 29, 2007