The set up to a joke; when one asks what it is, it sounds like, "What's Up Dog" to which you reply, "Not Much, You?" Or something like that. The joke became wildly popular due to it's use in a 2006 episode of The Office called, "The Secret".
Hey, did you hear about that updog poisoning in New Mexico?

What's Updog?

Not much, you?
by X040KL1M December 17, 2021
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He actually managed to pull this off, what an updog.
by cytoex November 12, 2021
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Updog is a joke like Ligma or Bofa in which one person would ask for updog or ask if they know what updog is and the receiver will reply with ("What's updog?") and will be utterly disappointed when they fell for that obvious joke.
Guy: I came on this website to find out what Updog is and it won't even tell me...
by BiggieOunce February 15, 2019
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updog is the amount of death of dogs that happen each 15 days, if the updog is more then 50 % you should run fast.
hey the updog is high, we need to move out
by the only joe papa November 14, 2022
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What you always smell every once in a while. Also known for being extremely unfunny.
Jimmy: It smells like updog in here.
Mark: What's updog?
Jimmy: Nothing much, what's up with you, dog?
Mark: Har har har.
by AshtyBoi August 13, 2021
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A word that randomly appears in a sentence so that the victim asks what it is. A play on words that refers to saying "what's up dog?".
Pee: Have you heard of the new updog?
Obama: what's updog?
Pee: not much, you?
Obama: ̴̡̨̛̜͎̘͍̪̭̖̳̠͈̰͎̐̇̎̈́͂̂̕̚ ̴̼̣̓̑̓̿͒͛̐́̀̚̕͝ ̴͙̞͇̹̱͍̖͒͐̇́͂͂̌̓̃ ̧̩̲͔̦̭̝̲͚̫̞̫̺̀̈ ̢̢͉̝̰͓̻̖̹̘͈̭̗͌͊̈̆͘͝ͅ ̢̹̝̼͚͚̗̘̰͕̮̖̭̲̲̈͛̆ ̶̨͚̳̖̦̺̻̲̳̼̈́̌̀͋͘ ̹͚̺̦̠̈́̐̍͑̎̈͊́̑̂͑̄͂̎͠ ̶̞̝͕͚͈͈̮̥̗͍̿͜ͅ ̼̌͗̋͋̊̈́͒̏̕͠ ̵̢̞͈̱̱͚͎͕͚̰̖͕̥̭̯͐̓̐̀̃͆́ ̛̩͇̟̼̞͚̭͙͔̜̞͎̐̆̄͋̾̇͆̓̕͝ ̨̖̹̖͙̣̮͇͕̭̎̔̃͒́̄̉̏̐̊̚͝͝ ̶̫̱̤̑̉̔̐͘ͅ ̶͈̔̉̎͐͘͘͠͝ ̶̢̧̡̲̱̰̦͇̹̬͙̗́͘͜ ̗̍̈́̇̿ ̶̡̧̜̫̪̺͉͎̤̟̗̿͂̔́̆̔͑̇͜ͅ
by secksman2 March 14, 2021
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