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1.
to be intoxicated by alcohol.
or alcohol itself.
bruh i'm sooo twizz!!

Yo where the twizz at?!?!
by Krazy Clean January 04, 2011
 
2.
Lady jizz
twat jizz
That girl i met at the bar last night turned out to be a real freak. she got twizz all over my new sheets.
by The Nate. May 23, 2012
 
3.
1. (v) To jizz on someone via twitter.
2. (n) The twitter jizz itself.
joebow696: @lizabeach05 8======D~~~~~
lizabeach05: I can't believe @joebow696 just twizzed on me!

---------

lizabeach05: Now my phone is sticky from all that twizz.
by dbeach January 20, 2010
 
4.
(Adj.) Used to describe something that is mediocre.
Sub-par
Lacking
"DUDE, THAT MOVIE RULED!"
"You kidding me? That shit was hella twizz, man."
by Kniggah June 03, 2007
 
5.
A Teen that plays a online game called counter strike :condition zero.He is a pro at the game and when he kills some1 he says "Go 2 Sleep" and owns with Deagles and Usps. He Loves Ak47 more than an M4A1, aka M16
Some Noob:

Damn TwiZZ how u see me around that corner!! OMG!! u prefired me wat a cheater!!

TwiZZ:

Go 2 sleep, you scrub.
by TwiZZ July 29, 2006