The process of getting completely and totaly wasted. Usually to the point where you either A) black out, dont remember, end up with two rico suaves in your dads car, pass out still in your boots, lose your car, purse, mind, etc.
The effect of consuming a combination of alcohol and at least one other substance (most commonly marijuana, although prescription pain medication may be used as a substitute if you have exhausted your weed supply) Common symptoms that you are twasted are slurred speech, heightened emotional state, repeatedly stating in a high pitched voice that you are "Twasted!". No future recollection of the event. Embarrassing photos soon follow.