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Uptown Manhattan, where numbers are used to define streets, not names. Everything above 14th street, more or less. Meaningless jive area, doesn't need to exist.

Everything except New A-Town in Manhattan is "The Numbers"
Guy one: I ain't goin all the way to fourty-deuce, I am staying away from the numbers.

Guy two: Word, screw them. New A-Town pride!
by atomic jerk December 21, 2005
A mysterious sequence of numbers that keeps appearing, either in fully or individually, on the American hit TV drama Lost. The sequence is 4-8-15-16-23-42.
"Wait, that metronome has '108' on it! Isn't that the sum of the Numbers?"
by Shay Guy October 23, 2006
The best. A phrase used when an act, object or person produces 1. positive financial return; 2. positive outcome; 3. when situations occur allowing for gain
Example 1.
"I don't know how to tell you this, but I'm kind of a big deal. You could say I'm the numbers of Napa Valley."

Example 2.
"We finished 10 surgeries by 5pm! That's the numbers!"
(The surgeon completed a large number of cases in a short amount of time, thus leading to an increase in profit for the hospital and surgeon. The numbers.)
by Pistol Layman August 28, 2011