Take it in the ass Share definition Flag 1) To express disappointment 2) Slang expression for an unfair/unfortunate event 1) Jeremy took it in the ass on that. 2) Paul took it in the ass when he invested in Worldcom stock Take it in the ass by BIATCH551 March 15, 2005 0 0 Get merch Get the Take it in the ass mug. Buy Now β $32.95 See more merch