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Similar to "get lost" or "take a hike," TIWYSI is a wildly popular expression meaning "you annoy me and I want you to go far away from this place where we are standing."
Attractive middle-aged man to a group of troublemakers congregating in front of his home: "Hey - take it where you shake it!"
by Bob43 March 17, 2008

Words related to Take it where you shake it

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Go away, but not literally to the place where you shake "it".
"Can I bum a smoke?"
"Dude, take it where you shake it"
by takershaker March 12, 2008