2 definitions by Bob43

Top Definition
Similar to "get lost" or "take a hike," TIWYSI is a wildly popular expression meaning "you annoy me and I want you to go far away from this place where we are standing."
Attractive middle-aged man to a group of troublemakers congregating in front of his home: "Hey - take it where you shake it!"
by Bob43 March 17, 2008
to become upset, usually out of proportion to the situation.
You: "C'mon, hurry up, I like to arrive at the movies at least 30 minutes early so I can Scotchgard my seat!"
Your friend: "Dude, don't get your skivvies in a bunch!"

You post a detailed analysis of a Star Trek episode, and someone leaves a disagreeing comment, causing you to write a 10,000-word essay defending your expertise. Someone then comments "Don't get your skivvies in a bunch."
by Bob43 August 11, 2010

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