Typically used on the east coast from Georgia down to Ohio. Taking off essentially means that you have just taken several hits of a joint. Take off is the act of getting stoned.
Person 1: “hey bro do you wanna take off right now?”

Person 2: “let’s do it man, let me grind these bud and roll it bro!”
by Twotenor December 21, 2021
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Taking a piss off the Hollywood sign either is protesting the perfection wanted of people or physically urinating off said sign.
Man:”I went and got a drink.”
Man 2: “Oh no.”
Man: “Yeah I ended up Taking a piss off the Hollywood sign.”
Man 2: “Protesting?”
Man: “No... literally.”
by Actually It Is *insert thing* September 17, 2019
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The act of leaning far forward whilst sitting on the toilet to help ease out a particularly difficult/large stool
“Mate that was terrible, I’m all backed up, it was so bad I was leaning forward like a goose taking off trying to squeeze that one out”
by TheAntiDote2019 July 11, 2023
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To retaliate against an oppressor with little, if any, regard for them.
In order to free ourselves, we must take off the white gloves
by Heyitsj000 November 9, 2020
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