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1.
A term to describe a very beautiful temptress with a sexually transmitted disease.
"I wouldn't do that dude, she looks tasty but she is syphilicious."
by Drifter December 02, 2003
 
2.
Because Syphilis should have an adjective hybrid word describng taste.
Wiley: Yo, man. That hoe was TIGHT!

Bobby: Yeah, but her vag was syphilicious.
by KeriFTW December 07, 2006
 
3.
A style that would usually be ugly, bar the fact it looks good on someone.

Someone who sleeps around a lot, Is probably disease ridden, but still known as a great fuck.
"Eewww.. That leopard print leotard is syphilicious"

" I cant believe she tapped that... Everyone knows hes syphilicious"
by Adele S February 08, 2007
 
4.
A girl who's a slut, but thinks she's hot, and also has syphilis.
Person 1: Dude, do you see that girl?
Person 2: Oh, dude, she's a slut and has syphilis
Person 1: What's her name?
Person 2: I think her names Alicia
Person 1: Oh that girl, ewww. She's loose.
Person 2: Yeah. definitely syphilicious
by EP et moi May 15, 2007