Top Definition
A description of an unusual, socially nonconforming girl stemming from Jerry Spinelli's book "Stargirl." Girls with Stargirlitis can exhibit any number of eccentric traits such as a love of comic books, a multitude of piercings or tattoos, unusual clothing (but generally not goth-type clothing) or carrying around small pet rodents. Unlike stereotypes of emo or goth people, girls with Stargirlitis are mostly happy. Almost all girls with Stargirlitis are right-brained and artistic.
Jerry: That girl has purple hair and sleeps with a blankie. I bet she has Stargirlitis.

Leo: That's so hot.
by TheBestDinosaur February 11, 2010

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