Top Definition
Noun: Halloween costume for great-looking women.

Derived from the words "slutty buffalo," because Seffalo ("sexy buffalo") sounded too much like a horrible infection. Costume consists of furry hat with horns, furry skirt, and furry leg warmers. Perfect for America themed Halloween parties because buffalo and sluttiness are very American.
Those sluffalo look like slutty buffalo!

I love Halloween because of all of the sluffalo running around.

That herd of sluffalo is HOT!
by Ween2011 October 13, 2011
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