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1.
When you have high expectations of/from something/someone and they let you down.

Background: Based on the fascinating twist in M. Night Shymalan's The Sixth Sense vs. the big letdown and predictability of The Village
a. Pete did a shyamalan on me for the technology section of our new business plan.

b. Pete is shymalanesque
by Anish Ratnam February 22, 2005
 
2.
When someone fucks up doing something.
The director of the "Last Air Bender" Shyamalaned it.
by Shadowmech04 July 22, 2010
 
3.
A handjob with a twist right at the moment of climax. The result is painful and ruins a normally enjoyable experience, much like an M. Night Shyamalan film.

handjob
Crazy bitch surprised me with a Shyamalan during a handy, fucked up my nut. It was worse than Airbender cause i couldnt get my $10 back.
by DisposablePal March 25, 2011
 
4.
A Shyamalan can be used to describe a girl who looks great from behind however upon seeing the front of her, you are horrified at your findings (the twist!).
That girl I sat behind in my Spin class looked hot, but when she reached back for her water bottle, she was a Shyamalan; what a twist!
by Gellikit October 26, 2010