Top Definition
Slang term for the drug Midazolam, a potent, fast acting benzodiazepine used for acute pain relief, before medical procedures, and in some cases terminal sedation in cancer patients. The term Rusty Jane comes from the drug's ability to sometimes cause mild inter-ocular bleeding, causing the patient to see everything in a pink or red hue.
The doctor gave me some Rusty Jane before surgery. Trust your pain to Rusty Jane.
by YerluvinunclePaul December 21, 2010
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