ROFLmouth: a condition resulting from the overuse of the muscles in the face, namely the ones involved with smiling and/or laughing. Symptoms include acute pain, tendonitis, and TMJ. ROFLmouth is usually the result of either comedic situations or the inhalation of, <ahem> certain plant extracts. (Usually some combination of the two) ROFLmouth is a combination of the acronym R.O.F.L.M.A.O (Rolling On the Floor Laughing My Ass Off) and the word mouth. It MUST be spelled with the first four letters in caps.
Holy shit! I got ROFLmouth from watching The Daniel Giuditta Progrum on Youtube!
by sharkman9k December 07, 2009