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1. A saying started by the Pink Puffball himself Kirby! In the anime Kirby would always say Puyo!

2. Also used in Kirby related in role plays to simulate Kirby's curious actions!

3. Some go fan tardish and say poyo all the time w/o any meaning.
King Dedede: Imma squash dat dere Kirbeh!
Kirby: Puyo?
by Proshi January 30, 2012