Top Definition
1. When the real world hits you like a slap to the face after a fierce masturbation session.
Joe: "I beat off with birthday cake frosting... I hated myself and wanted to die..."

Terry: " Sounds like Post Masturbation Depression Syndrome to me. Don't sweat it, bro. It's normal. But that IS fucked up..."
by mbarfiel February 04, 2010

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