To take pills like candy, usually illegal drugs. Used in well known rap songs like Antidote by Travis Scott
"poppin pills is all we know" -Travis Scott, Antidote.
by Jsullivan704 December 7, 2015
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PPA ( Pill Poppin Animal)
From Lil Waynes song (Pill popping animal)

i'm a pill poppin animal
syrup sippin nigga
syrup syrup sippin nigga
syrup syrup sippin nigga
by Kevin Garnett the greatest October 13, 2009
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