Pneumonoultramicroscopicsilicopenisvolcanoconiosis meaning: A lung disease caused by the inhalation of very fine silica dust, causing inflammation in the lungs.

It has 45 letters that put it together. It a word commonly said to be the longest word in the English dictionary.

noun: (NOO-muh-noh-UL-truh-MY-kruh-SKOP-ik-SIL-i-koh-vol-KAY-no-KOH-nee-O-sis)
Miner - "I've been working in that mine for far too long. The doctors told me I am going to die of a lung disease caused by the inhalation of very fine silica dust, causing inflammation in the lungs. It's called Pneumonoultramicroscopicsilicopenisvolcanoconiosis."

Concerned Person - "Oh my, how did you even pronounce that?"
by lolatJESS July 24, 2009
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