Top Definition
The twilight zone of male female relationships. When a male is interested in a female for a long time and the female believes that the male is a "good friend." Closely associated with the phrase "Fuck My Life."
--Tell me Wilhelm, how is your courtship of young Rebecca?
--Oh Thadeus, I have become her "Permafriend".
--That is most suckage, most suckage indeed.
by Siamese Olsen Twin From Mars November 19, 2010
friends that are both permafried together or friends that always get high together
"Fred, Amelia, Andy, and Michael are permafriends"
"yeah theyre always doing stupid shit together"
by permafriend July 19, 2015

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