Period Hole Share definition Flag The hole used by men while women are on their periods. Also known as the asshole. Karen was bitchin' out and Bob knew why. So he fucked her in the period hole and all was well. Period Hole by Yeah brooooooooooooooo January 10, 2011 0 0 Get merch Get the Period Hole mug. Buy Now — $32.95 See more merch