1) a popular Spanish nicknames for young boys in any part of Spain or Latin America. It is a nickname for the name 'Jose'.
2) vagina in Filipino language. May also be called alternatively as 'pekpek'.
2) Oh shit, ang sarap pasukin ang 'titi' ko sa 'pepe' mo!
Oh shit, it's so pleasureable to insert my 'penis' in your 'vagina'!
Bill: Personally, I would let that fine young woman suck my pepe. Then, I would ejaculate my load of semen into her vagina.
Juanita: Shut your fucking face! Chu' ain't no cholo ya dumb fucking cracka'.