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1.
Oup
say instead of laughing at something, or after something funny or ironic happens
the kid was saying how funny it would be if someone fell down the stairs, then some fat kid trips and falls down the stairs. the kid would say 'oup'!
by cracka AD November 29, 2003
 
2.
An expression of regret or loss; suitable in situations when something you once loved is lost, misplaced, taken.
Similar to the common term "oops", but with a more specific meaning.

The phrase originated in the boondocks of Ohio.
I lost a studcupcake I once had. Oups.
by Henry Stopsign March 19, 2013