The asshole of upstate New York. Ironically, the waste water treatment facility of this town is top-notch due to the septic shit the residents pump out.
Man am I thrilled I moved away from those self-righteous HIV+ whores that went to Nisky. AUGHH! A GIANT AMOEBA!
by AlphaTard January 01, 2004
A pile of shit somewhere in upstate New York

Slang: A smelly restroom
1) Sally: What is that brown lumpy thing?
Bob: That is Niskayuna

2) Bobbert walked into the Niskayuna and suffocated
by John November 27, 2003

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