Top Definition
Abbreviation meaning "No YOU Shut Up!!!", used as a response to "STFU" (Shut The F*ck Up).
Bloke 1 = STFU, retard!
Bloke 2 = NYSU, arsehole!
Bloke 1 = Huh?
by Yoghurt Pot January 27, 2008
4 Words related to NYSU

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