Originating from video games, it stands for non-player character. It has a double-edged meaning:

To the person using the term, they are advertising that they have a better sense of perspective and understanding to the world than other people in society.

To everyone listening to that person use that term unironically, they know that the person has a massive empathy deficit and is at best woefully emotionally under-developed, and at worst a raging sociopath.
“What about this dude, Josh Smith?”

“Yeah… I had a quick conversation with him for a few minutes, and he used ‘NPC’ unironically.”

“Oof, that's bad. Maybe he's young?”

“He also referred to women as ‘females’.”

“Oh, no. Okay, bin him. At the very least we'll save on the sexual harassment lawsuits.”
by tariqk November 28, 2022
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A non player character, aka those people who fit in way too well.
Person 1: “Did you ever talk to Adam, he’s such an npc.”
Person 2: “Yea that guy is WAY too average.”
by CFTN August 12, 2019
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Npc or bot have the same meaning. This means a person who is considered a background character or an insignificant person who acts, talks or walks like an npc video game character. The meaning npc can also be literal, like an npc who is stuck in the matrix and does whatever is told to that person like an npc in a video game.
Kid 1: walks normally like a human being would. Kid 2: NPC NPC!!!!!!
Kid 2: *Waves* Kid 1: NPC
by oogwayheigweimasteryoda December 19, 2022
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you either unpopular, living under a rock, or u are like super quiet and weird. Personally don't take this type of assault.
"dude you're literally an NPC."
answer: "go jump off a twin tower and sug my cockis you fuggly unwanted peice of dog doo. You're so short i can literally use u as an armrest, you literally need to use toddler's shoes, u probably still breastfeed. You're not popular get it into ur microscopic brain. U are literally an NPC, u copy everyone's actions. At Least i have a life, unlike u who just follows around the popular kids like a fucking dog."
by cvmcslvt November 14, 2022
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A programmed character in a videogame that have reactions programmed into them.

Also used to describe people who blindly follow a group/group identity/ideology with such dogma it makes BTS stans look sane. They have no ability to think logically/rationally/critically. They regurgitate things they read in Facebook articles and spend a lot of their time on social media since they have nothing better to do (specifically Facebook).
Person 1: I think we should have universal healthcare for all.
person 2: IF YOU DONT LIKE IT HERE THEN LEAVE YOU COMMUNIST
person 1: I don't think you realize just how much this could benefit you and everyone around you
Person 2: ITS COMMUNISM AND I DONT WANT MY TAXES GOING TOWARDS YOUR HEALTHCARE
Person 1: You clearly don't know what communism is, go read a book you NPC
Person 2: THE ONLY BOOK I WILL READ IS THE BIBLE. FUCK YOU COMMIE
by Xeniful March 6, 2022
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a dumb bitch who thinks they're different even though they're just some ugly edgelord who's built like shane dawson and looks like a discombobulated dick
weirdo: comments "W" on a racist post
person with common sense replies to the weirdos comment: "you fucking NPC kys"
by manu rios July 4, 2022
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