Top Definition
My best friend (who is sick and tired of the term bff.) A friend of exceptional caliber. One who is like family.
You just saved my life, you really are my beef. My beef just let me borrow his car, no questions asked.
by SLAY Co. Inc. February 10, 2015
1 more definition
5 Words related to My Beef
1. Expressing sorrow for a wrongdoing
2. my bad
1. Out on the court playing b-ball, someone shoots and another player slaps his face after a failed attempt to block the shot. That person then say:
1. Big Mike - Damn son. My beef.
2. R.O.B. - It's aight. I got a spare in the trunk.
by mike+rob show April 02, 2007

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