Top Definition
The best teacher in the history of television. She drives a magic school bus. It's a wonder she and the other kids are still alive given what the bus has seen and done.
Ralphie: You did pass your ladybug driving test, right?
Ms. Frizzle: With flying colors!
by Secret Agent: Dog November 23, 2014
A foul creature formed when a donkey mates with a deceased body. It can stare into your soul and lurks the cafeteria or bus to prey on children.
Oh Shit! Ms. Frizzle's walking toward us!
by TheRagingTaco April 14, 2015

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