To get completely beaten by someone in any activity or way
Damn, John really mother fucked Eric in that game of pool!
by Josh Venne June 9, 2006
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The essence of horniness or want to have sex. The ability to have sex.
"Damn, I'd bang the mothering fuck out of her!"
by King Waffle January 7, 2010
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As used by Kim Catrall's character, Samantha Jones, in an episode of "Sex and the City"; a situation of extreme misfortune or catastrophe, usually regarding relationship problems, wardrobe malfunctions, or unintended pregnancy. Those involved in "shit mother fucker fuck shit situations" often find it hard to explain themselves when the truth comes out and then find it even harder to repair the damage they cause.
Lacey: "You'll never believe what happened to me yesterday"

Sue: "Bryan found out you were cheating on him with his best friend, didn't he?"

Lacey: "Yep, talk about a shit mother fucker fuck shit situation."
by Chainsaw22 September 14, 2007
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To yell profanities at a jury while you are on trial.
Defendant: All y'all piece of shit mother fuckers on this jury are gonna die.

Judge: thank you mother fucking the jury, but we still need to finish opening statements.

Jury: I don't think that is necessary, we find the defendant guilty on all charges.
by Humphreyneworleans January 19, 2017
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Drunk, hooch guzzler, wine-o, lush, ethanol challenged

Life of the party. Always the funniest person at the party or bon fire. One with the Most experience and holding their liquor either by drinking the most over long period of time or had the harder party days in their younger years.
Liquor is a spirit, spirit is a ghost. That makes me a mother fucking Ghostbuster
by Plumbsavvy May 17, 2019
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