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The absolute opposite of negative, even more so than positive.
Franklin: "Dude, she has lots of money and huge titties!"
Stuart Skauge: "Megative!"
by Tween October 06, 2005
Something extremely adverse (see: negative).
The torrential rains had a megative effect on my golf game.

I hope my addition to the Urban Dictionary does not megatively affect Roy Blount's on-going efforts to be honored in a similar fashion.
by Tad McDonald February 02, 2009
When something is extremly negative.
It was megative 25 yesterday.
by Nobody86718 January 25, 2011