Top Definition
An involuntary execution of every bodily function all at once. such as sneezing, vomiting, bleeding, crying, farting, orgasm , sweating, defecating, salivating, urinating, hiccuping, having a seizure, etc. Generally associated with extreme stress.
That band is so awesome they'll make you mastigulate!

He tried to be smooth while talking to the super hot girl but instead he mastigulated.
by Remo "Uzi" Gwaldabi March 17, 2011

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