The immediate feeling you get when you just put a large amount of time of work into something, something that you crafted yourself, something that is special to you... only to have all of it suddenly squandered away at the very end.

Named after the game Mass Effect 3, which arguably has the worst ending in video game history.
I once had a puppy I bought and nurtured all by myself. He was growing into a healthy dog; he was very happy and we had so much fun. Then some horrible person decided to kill him and he got away with it. I Mass Effect 3'd for the rest of the year.
by RROTM March 12, 2012
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A Birth control supplement that will be introduced to Society on March 6th 2012, Co-Created By Bioware/EA.
"BF" - I didn't buy any condoms

"GF" - WHY NOT?

"BF" - Mass Effect 3

"GF" - WTF IS THAT?

"BF" - Your Replacement
by ShWaY is a boss January 28, 2012
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A famous person on Funny Pics app for Iphone. Quite possibly the coolest being that has ever existed. He likes his bitches blue.
Dude, Mass Effect nerd talked to me.... O.O
by mortified__penguin October 29, 2010
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"Have you played the new sequel to the classic hit video game Mass Effect: 3, Mass Effect: Andromeda"
"It's me, Eddie Murphy. Fuck you"
by Fairbanks. May 20, 2020
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An excellant award winning AAA scifi video game developed by Bioware and published by EA. In Mass Effect 3 you play as Commander Shepard a Spectre who must save the galaxy from a Reaper invasion. Hundreds of critics praised Mass Effect 3 and it scored dozens of perfect reviews. Unfortunatly the game was hated by thousands of Mass Effect fans because of the sad ending. Many claimed that the last sad ten minutes of the twenty+ hour experience destroyed the entire game. These fans were so disgruntled by the depressing ending that they created the Retake Mass Effect movement. Many developers were harrassed, hundreds of petitions were signed and Bioware was even reported to the Better Buisness Bureau by a Retake Mass Effect member. Eventually Bioware gave into the whining legions of Retake Mass Effect members. Extended cut a free DLC that adressed the plotholes and cliff hangers was released, but this didn't satisfy infact it just made the whiners even more angry because the ending was still sad. Now Mass Effect 3 a brilliant game will just be remembered as a big disapointment by the gaming community.
Critics: Mass Effect 3 is an exceptional game!

Gamerz: MASS EFFECT 3 SUKS ASS CUZ ENDING!!!!1
by normalgamer November 14, 2012
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A soon to be kick ass game that falls from space and apparently lands in 150 foot tall trees in Santa Cruz.
Nerdy Fan 1: Hey dude, climb up that tree and get the mass effect 3 space edition for me all the way at the top.

Nerdy Fan 2: Can it wait for a bit, I'm in the middle of some calibrations.

Nerdy Fan 3: Sorry, I have to go.
by Moist Supreme February 29, 2012
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A game made by BioWare, a Ea Partnership company. It takes place in the future and you get to play the role as Commander Shepard. It is a lesser of Mass effect #1, It is also a sequel to Mass Effect
'Wow I just Got Mass Effect 2 and they changed the ammo from infinite to finite!? How could they?' exclaimed the boy
by Spike L September 27, 2010
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