A lady, often older, who is known for "helping" struggling men/boys loose their virginty
the female version of a virginkiller
made famous on the show How I Met Your Mother. Whom the character Barney lost his virginity too.
Guy1: Wow! You haven't lost your virginity!? you're 20 something!
Guy2: Yeah...its been hard you know.
Guy1: Allright, I'll get you hooked up with the Manmaker and she will help you out.