The rape of a man by another man.
That guy sitting over there has a look as if he wants to Man Fuck me.
by Alex Den Hartog May 11, 2010
Sex performed by a man with another man or woman.
(Male or Female)I am going out tonight hunting for a manfuck.
Penetration with a penis, not a toy, carried out by a man on either sex.
by Nuttier July 31, 2006
An exclamation originating in the town of c-port. Between several guys, the term means, "oh shit!" The phrase is basically a bigger OH SHIT.
"What are we gonna do tonight?"
"I don't know."
"man FUCK."
by Skrempy January 01, 2006

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