Top Definition
A mainstream whore is one whom follows almost every single trendy thing they can, and changes as new things come out, or older things come back.
Mary: I mean I used to like the Jonas Brothers, but then I moved onto Justin Bieber. I am absolutely in love with One Direction now though, even though I only like one of their songs.

Susy: You are such a mainstream whore.
by William Sharks pear July 08, 2012
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