Very mad, but typically refers to someone in the public eye. Of course, as the very idea of putting frogs in a box is eccentric to say the least, one who is very mad can be said to be; As mad as a box of frogs
That Ronan Keating - He's as mad a s a box of frogs.
by Tanky November 08, 2003
to be out your fucking tree,a coplete fruit loop
president bush is as mad as a box of frogs
by STIK February 08, 2006