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1.
Someone who has Lyme Disease
Even though I am a suffering Lymie, I will not let that ruin my life.
by AlwaysHaveHope March 21, 2007
 
2.
Unknown origins. It is used commonly to describe the lowest form of human beings, in the entire world, the English.
The Queen is a faggot arse lymie!
by TheIrishRover November 23, 2004