Top Definition
Luke Disease is belittlement of the penis, erectile dysfunction, gayness and general rtardness. There is no known cure for this, sufferers are too rtarded and gay to accept a cure.
Known sufferers: Luke
Jole: "OMG, That My Rtarded friend was acting all gay today, and in the changing room, I saw his cock, it was the size of a PEA. He told me he had erectile dysfunction O_O"

by Daemonius :] July 25, 2008
6 Words related to Luke Disease

Free Daily Email

Type your email address below to get our free Urban Word of the Day every morning!

Emails are sent from We'll never spam you.