Luke Disease is belittlement of the penis, erectile dysfunction, gayness and general rtardness. There is no known cure for this, sufferers are too rtarded and gay to accept a cure.
Known sufferers: Luke
Jole: "OMG, That My Rtarded friend was acting all gay today, and in the changing room, I saw his cock, it was the size of a PEA. He told me he had erectile dysfunction O_O"
DAVID: "OMFGZ, HE HAZ LUKE DISEASE!"