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1.
the state of being pushed over the edge of sanity and having a complete and utter freak out or mental/emotional breakdown
1. Dude your Losing your shit.

2. On a day to day basis I tip toe the line of losing my shit.

3. If you don't shut the fuck I'm gonna lose my shit and punch babies.

4. DUDE MATT I'M ABOUT TO LOSE MY FUCKING SHIT.
by mau810 April 11, 2011
37 6
 
2.
the state of mental breakdown resulting from near overdose of hallucinogens.
Dude, remember when you were on the verge of losing your shit after eating that handful of Nixon Candy and ranted for an hour about the destruction and repair of your favorite headphones?
by hop December 14, 2003
10 13