Top Definition
Abbreviation of Laugh Until We All Piss Ourselves, only to be used in extreme circumstances of hilarity
If used lighly, you may cause severe damage to your popularity
John: Omomg, guess what?
Steve: Hear what?
John: Fred tried to jump over the river on his bike, his bike caught a bush, he went spinning off and crashed into the river, and his bike got thrown out in front of a truck!
Steve: LUWAPO!
by WobbyTwo January 06, 2011

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