A hulking vehicle who often hits those who are in need of something drastic in their lives. Often that change is paralysis or death. You probably know somebody who was hit by one.
That fucker got hit by the Jesus Bus REAL good.
by mickeyrourke February 25, 2005
Top Definition
The spiritual equivalent of the city bus that comes through hospitals and picks up the terminally ill usually during the night. When it is said that the patient has his metrocard (ticket) ready, it means he's knocking on heavens door.
Mr. Leff is looking like hell, I bet the Jesus Bus is gonna come around for him soon.
by Leysie January 14, 2008
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