to have a lack of confidence pertaining to a school subject, leading the student to try to avoid getting called on by all means. Usually brought on by the teacher staring at you until you get the right answer. Has nothing to do with the president.
Symptoms include:
Nervousness
Seat slouching
reddening of the face
lack of confidence
I have had Jefferson's Syndrome ever since the teacher asked my to explain why the physics demo worked... followed by a five minute stare-down
by Isaac Semelwies March 21, 2013
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When white men secretly want to have sex with black women.
You know deep down John Boy is a chocoholic who wants to have sex with Shanika. Yup, he's got a case of Thomas Jefferson Syndrome alright.
by Po Black Pussy October 23, 2008
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