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1.
Janey Mac is widely used in Ireland as a euphemism for Jesus Christ, to avoid taking his name in vain. See also: Jakers and James's Street.
Janey Mac, what the hell were you thinking?
by Matt Madra April 26, 2008
 
2.
Wow! An exclamation usually used with 'Good Golly, Miss Mollie...'
Good Golly, Miss Mollie and Janey Mac!
by PMacSwiney December 02, 2006