Top Definition
'jrs' is an acronym for 'Just Routine Shit'...
2pac: Holla homie...wadup?
Biggie: jrs homie...

The above conversation is clear...likewise, if yo' homie or anyone hollers at ya sayin' "wadup?", then if ya aint up with anything new, then yo' reply must be "jrs"....
by stranga September 04, 2006

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