IBS or irritable Biden syndrome affects the carrier with a complete lack of bowel control. Folks literally can’t stop sh@tting themselves over the fact that Joe Biden is president.
Let’s go Brandon

“Dude, I think you’ve got IBS (Irritable Biden syndrome)
by kacz December 26, 2022
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An affliction that causes an immediate raging boner when looking at any attractive woman.
DUDE 1-"What's up with that snake in Jims pants?" DUDE 2-"Poor guy.He has I.P.S.(Irritable Penis Syndrome)"
by Sky49 November 18, 2009
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irritable balls all the time. its like peeling gum off a hot side walk.
There is no none cure for irritable balls syndrome (IBS), your not alone.
by Genis85 August 27, 2011
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When someone's jaw swings back and forth after going mental on Pills, MDMA, MKAT or Amphetamines.
Check out Paddy's irritable jowl syndrome! He must have necked at least 3 blue Lacosts.
by dawbzylad June 19, 2011
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The annoying discomfort resulting from your thong rubbing your booty the wrong way.
Lisa: “You don’t look happy, what’s wrong?.”

Cynthia: “I bought this lace-trimmed thong because it was really cute, but it’s giving me a terrible case of Irritable Thong Syndrome (ITS).”
by kraftgirl September 30, 2009
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A condition in older dogs where they get real grumpy and and get aggravated easily.
My old dog who has continuous arthritic pain is always grumpy and suffers from irritable bow-wow syndrome.
by weasel990 July 11, 2010
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What Shrek screams at donkey out of vexation when Shrek explained to him that ogres are like onions, but donkey kept blabbering on about cakes and parfait.
For your information, there's a lot more to ogres than people think.
Donkey: Example?
Shrek: Example? Okay, um, ogres are like onions.
Donkey: Sniffs They stink?
Shrek: Yes-- No!
Donkey: They make you cry?
Shrek: No!
Donkey: You leave them out in the sun, they get all brown, start sproutin' little white hairs.
Shrek: No! Layers! Onions have layers. Ogres have layers. Onions have layers. You get it? We both have layers.

Donkey: Oh, you both have layers. Oh. Sniffs You know, not everybody likes onions. Cakes! Everybody loves cakes! Cakes have layers.
Shrek: I don't care what everyone likes. Ogres. Are not. Like cakes.
Donkey: You know what else everybody likes? Parfaits. Have you ever met a person, you say, "Hey, let's get some parfait," they say, "No, I don't like parfait"? Parfaits are delicious.
Shrek: No! You dense, irritating, miniature beast of burden! Ogres are like onions! End of story. Bye bye. See ya later.
by Rotten Turkey June 24, 2021
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