A disease in the category of mental retardation. The center of a mammal's brain is taken over by Dringi. The disease causes the host to always be irritable, as if there is a huge wooden thorn in their left foot. Typical side effects are a whooping cough and Mononucleosis for 17 years. There is only one creature known to have this unfortunate disease.
I am not feeling well. I think I have Irritable Barden Syndrome.
by 1011B January 30, 2014
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Blue balls make you angry, upset, agitated and irritable.

After getting aroused for a while and then not getting off is irritating.

If a girl is known for giving guys blue balls she can be labelled IBS.
Mitch "Yo, why are you sitting with your legs so wide apart and your belt undone?"

Corey "That tease Brandi gave me Irritable Ball Syndrome again."

Mitch "IBS, sucks to be you."
by Lawrencetown April 12, 2013
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This is the name for something that is putting alot of stress on your mind and causing you annoyance.
This job is giving me irritable brain syndrome!

She/He makes me feel like I have irritable brain syndrome!
by The Spooky Twigg October 29, 2004
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Irritable Project Syndrome (IPS)

Occurs when most members of a project team get extremely crabby and short-tempered due to shifting deadlines, impossible deliverables, inadequate resources, or insurmountable constraints. Symptoms include snarky comments, mean emails, shouting matches, escalations, increased absenteeism, sleeplessness, and catatonic withdrawal. Treatment can include alcohol, complaining/venting to your peers, turning off electronic devices, long vacations, and no longer giving a damn.
"Angel, I don't know how to tell you this, but I believe you suffer from Irritable Project Syndrome. But you don't have to suffer alone. "
by DanGarPrius October 21, 2016
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When you or your Scrabble opponent has so many vowels on their rack, they can't make a word on the board, or the only word that can be made is going to score very low. Complaining about having too many vowels and getting irritable reign over swapping a vowel tile and skipping a turn.
player #1: your turn.
player #2: dude, I can't even make a word, I have too many vowels.
player #1: swap some tiles, then.
player #2: no, it's ok. I will just make this two letter word and get a crappy point score.
player #1: sounds like you are suffering from Irritable Vowel Syndrome.
by scrabble girl April 28, 2010
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A low pitched howling noise someone with IBS makes when they are feeling some kind of discomfort, often emotional. It can also be used to accentuate a sentence with little to no effect. The noise can be be best described as the sound that a dinosaur would make when hit by a train.
1: Zack: Joe, you're retarded.
Joe: HNNNNNGGGGGGGG

2: Mark: Man, I'm awesome at this HHNNNNGGGGG.
Jack: Nice Irritable Bowel Howl, there.
by srj1224 February 3, 2010
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When someone is just irritating you and your should entirely and you want to blow the whole world up.
Dude, you irritate my soul.
by glittersparkles August 17, 2017
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